Combat:
8. Spells, such as heals, will land on whomever was targeted when the spell was initiated, not on whom you are targeting when it actually finishes casting and lands. Thus, you can use the Assist function (mapped to "F" by default) to quickly switch from doing DPS or debuffing of a mob to healing the mob's target then back to attacking the mob in just three keystrokes ~From Voxin
A quicker way to do this same thing is to enable "Target Forwarding" in the combat options. If you are a minstrel you can target the mob to sing your damage songs at him but also sing your healing songs at whoever the mob is targetting. Or vice versa, target your fellowship's main tank for heals any all your offensive spells get forwarded to his/her target.
When target forwarding is enabled its also a good idea to enable showing your target's target.