I always feel bad for the Morvul-Defilers in the Lumul-nar 3-man that say something along the lines of "Why do you torment us in our homes?" Sure, they may be evil vampire/bat-people, but they sound so sad when we barge in and slaughter them all.
I've also completed Hytbold on three characters so far, mainly so I can free whoever I wrongly accused of trying to murder the Reeve. Letting them rot in jail indefinitely is just too much for my conscience to bear!