I just completed some tests with Crossover 21.2 and LOTRO. I see no functional difference in LOTRO with Crossover 21.2 (21.2.0.33926) vs LOTRO with Crossover 21.1. So it's safe to upgrade, but there's no compelling reason to do so at least as far as LOTRO is concerned. Therefore, if you own Crossover 21.1 but don't currently have a subscription, there's no special need to buy a new Crossover subscription in order to upgrade to 21.2.